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Umetrics simca 14.1
Simca 14.1, supplied by Umetrics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/simca+14%2E1/simca+14+1/pmc12275879-75-8-10
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simca 14.1 - by Bioz Stars, 2026-09
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Recombinant:

Article Title: Exploring the flavor characteristics and key flavor-related metabolic pathways in sour congee of different foxtail millet varieties
Article Snippet: Sour congee is a traditional non-alcoholic fermented grain food in China; however, the flavor diversity in sour congee of different foxtail millet varieties and key flavor-related metabolic pathways have yet to be thoroughly evaluated.. This study analyzed the physicochemical properties, taste components, and aroma compounds of six millet varieties used in sour congee production.. Results showed that flavor differences arose from compound concentrations rather than types.

Article Title: Differences in odor-active compounds and non-volatile precursors between spray-dried and freeze-dried Spirulina platensis revealed by GC×GC-TOFMS-O and UPLC-MS/MS.
Article Snippet: The effects of freeze-drying and spray-drying on odorants and precursors in Spirulina platensis (Sp) cultivated in different environments (gj: glass jar; rp: raceway pond; cp: circular pond) were investigated.. Ninety-four odorants were identified, and hexanal, (Z)-4-decenal, (E, E)-2,4-decadienal, β-cyclocitral, β-ionone, dimethyl trisulfide exhibited higher flavor dilution factors (≥ 81).. Spray-drying increased pyrazines and terpenoids formation, enhancing roasted and seaweed-like odors, whereas freeze-drying retained higher levels of aldehydes and acids, causing fishy and rancid odors.

Article Title: Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Article Snippet: Soil organic carbon (SOC) sequestration is crucial in sustaining agroecosystem productivity.. However, the mechanism through which microbial functional gene assemblages and rhizosphere metabolites drive SOC sequestration remains elusive.. Ten-year field experiments examined how straw mulching (0 and 7500 kg ha 1) with nitrogen (0, 120, and 180 kg N ha 1) reshape microbial functional potential, drive soil carbon sequestration, and enhance annual crop productivity in the wheat–maize rotation system.

Article Title: Planthopper-induced volatiles suppress rice plant defense by targeting Os4CL5-dependent phenolamide biosynthesis.
Article Snippet: The mean weight of REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins p-Coumaric acid Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-98-4 N-Feruloylputrescine Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-13-3 Deposited data RNA-seq data This paper NCBI GEO: PRJNA1276156 Raw analysis data This paper; Mendeley Data https://doi.org/10.17632/c7ftgzyc84.1 Experimental models: Organisms/strains Rice strain (Minghui63) China Rice Data Center N/A Rice strain (Zhonghua11) Biogle Biotech Co., Ltd, Jiangsu, China N/A Rice strain (aoc mutant) Henan University N/A Rice strain (ospal6 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101768B06 Rice strain (os4cl5 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101529A08 Oligonucleotides Primers for quantitative real-time PCR This paper Table S5 Software and algorithms Primer 6 Premier Biosoft International, Palo Alto CA, USA http://www.premierbiosoft.com/primerdesign/ SPSS 26.0 IBM SPSS, Somers, NY, USA https://www.ibm.com SIMCA 14.1 Umetrics, Umeå, Sweden https://www.sartorius.com/en/products/process- analytical-technology/data-analytics-software/ mvda-software/simca Metaboanalyst 5.0 N/A https://www.metaboanalyst.ca/ ll OPEN ACCESS e1 Current Biology 35, 1–11.e1–e4, July 21, 2025 Article the BPH nymphs on one plant was considered as a biological replicate, and a total of 35-36 replicates were conducted for each treatment.

Article Title: An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy
Article Snippet: Principal component analysis (PCA) was conducted with SIMCA 14.1 (Umetrics AB, Umea, Sweden).

Article Title: Advancing freshness classification of freshly squeezed fruit juice via integrated multivariate analysis and machine learning approaches.
Article Snippet: In this study, multivariate analysis (MVA) and machine learning (ML), combined with UHPLC-HRMS, were used to evaluate the freshness of apples for juice production based on the analysis of freshly squeezed apple juice.. A total of eight stages of apple juice, representing varying levels of freshness, were examined.. Unsupervised MVA techniques, including PCA and Spearman rank correlation heatmap, revealed biochemical changes in the apple juice composition as rotten progressed.

Article Title: Metabolic dynamics of litchi pericarp and pulp during browning: Unraveling differential profiles through temporal clustering and untargeted metabolomics
Article Snippet: Chemometric modeling (PCA, OPLS-DA) was carried out using SIMCA 14.1 (Umetrics AB, Umeå, Sweden), with statistical significance assessed through nonparametric Mann–Whitney U tests ( P < 0.05) performed in SPSS 26.0 (SPSS Inc., Chicago, Illinois, USA).

Article Title: Physicochemical properties, aroma compounds, non-volatile metabolites and their potential correlation in Wickerhamomyces anomalus- fermented Sichuan-style sausage
Article Snippet: Principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed with SIMCA 14.1 (Umetrics, Umea, Sweden).

RNA Sequencing:

Article Title: Exploring the flavor characteristics and key flavor-related metabolic pathways in sour congee of different foxtail millet varieties
Article Snippet: Sour congee is a traditional non-alcoholic fermented grain food in China; however, the flavor diversity in sour congee of different foxtail millet varieties and key flavor-related metabolic pathways have yet to be thoroughly evaluated.. This study analyzed the physicochemical properties, taste components, and aroma compounds of six millet varieties used in sour congee production.. Results showed that flavor differences arose from compound concentrations rather than types.

Article Title: Differences in odor-active compounds and non-volatile precursors between spray-dried and freeze-dried Spirulina platensis revealed by GC×GC-TOFMS-O and UPLC-MS/MS.
Article Snippet: The effects of freeze-drying and spray-drying on odorants and precursors in Spirulina platensis (Sp) cultivated in different environments (gj: glass jar; rp: raceway pond; cp: circular pond) were investigated.. Ninety-four odorants were identified, and hexanal, (Z)-4-decenal, (E, E)-2,4-decadienal, β-cyclocitral, β-ionone, dimethyl trisulfide exhibited higher flavor dilution factors (≥ 81).. Spray-drying increased pyrazines and terpenoids formation, enhancing roasted and seaweed-like odors, whereas freeze-drying retained higher levels of aldehydes and acids, causing fishy and rancid odors.

Article Title: Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Article Snippet: Soil organic carbon (SOC) sequestration is crucial in sustaining agroecosystem productivity.. However, the mechanism through which microbial functional gene assemblages and rhizosphere metabolites drive SOC sequestration remains elusive.. Ten-year field experiments examined how straw mulching (0 and 7500 kg ha 1) with nitrogen (0, 120, and 180 kg N ha 1) reshape microbial functional potential, drive soil carbon sequestration, and enhance annual crop productivity in the wheat–maize rotation system.

Article Title: Planthopper-induced volatiles suppress rice plant defense by targeting Os4CL5-dependent phenolamide biosynthesis.
Article Snippet: The mean weight of REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins p-Coumaric acid Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-98-4 N-Feruloylputrescine Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-13-3 Deposited data RNA-seq data This paper NCBI GEO: PRJNA1276156 Raw analysis data This paper; Mendeley Data https://doi.org/10.17632/c7ftgzyc84.1 Experimental models: Organisms/strains Rice strain (Minghui63) China Rice Data Center N/A Rice strain (Zhonghua11) Biogle Biotech Co., Ltd, Jiangsu, China N/A Rice strain (aoc mutant) Henan University N/A Rice strain (ospal6 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101768B06 Rice strain (os4cl5 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101529A08 Oligonucleotides Primers for quantitative real-time PCR This paper Table S5 Software and algorithms Primer 6 Premier Biosoft International, Palo Alto CA, USA http://www.premierbiosoft.com/primerdesign/ SPSS 26.0 IBM SPSS, Somers, NY, USA https://www.ibm.com SIMCA 14.1 Umetrics, Umeå, Sweden https://www.sartorius.com/en/products/process- analytical-technology/data-analytics-software/ mvda-software/simca Metaboanalyst 5.0 N/A https://www.metaboanalyst.ca/ ll OPEN ACCESS e1 Current Biology 35, 1–11.e1–e4, July 21, 2025 Article the BPH nymphs on one plant was considered as a biological replicate, and a total of 35-36 replicates were conducted for each treatment.

Article Title: An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy
Article Snippet: Principal component analysis (PCA) was conducted with SIMCA 14.1 (Umetrics AB, Umea, Sweden).

Article Title: Advancing freshness classification of freshly squeezed fruit juice via integrated multivariate analysis and machine learning approaches.
Article Snippet: In this study, multivariate analysis (MVA) and machine learning (ML), combined with UHPLC-HRMS, were used to evaluate the freshness of apples for juice production based on the analysis of freshly squeezed apple juice.. A total of eight stages of apple juice, representing varying levels of freshness, were examined.. Unsupervised MVA techniques, including PCA and Spearman rank correlation heatmap, revealed biochemical changes in the apple juice composition as rotten progressed.

Article Title: Metabolic dynamics of litchi pericarp and pulp during browning: Unraveling differential profiles through temporal clustering and untargeted metabolomics
Article Snippet: Chemometric modeling (PCA, OPLS-DA) was carried out using SIMCA 14.1 (Umetrics AB, Umeå, Sweden), with statistical significance assessed through nonparametric Mann–Whitney U tests ( P < 0.05) performed in SPSS 26.0 (SPSS Inc., Chicago, Illinois, USA).

Article Title: Physicochemical properties, aroma compounds, non-volatile metabolites and their potential correlation in Wickerhamomyces anomalus- fermented Sichuan-style sausage
Article Snippet: Principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed with SIMCA 14.1 (Umetrics, Umea, Sweden).

Mutagenesis:

Article Title: Exploring the flavor characteristics and key flavor-related metabolic pathways in sour congee of different foxtail millet varieties
Article Snippet: Sour congee is a traditional non-alcoholic fermented grain food in China; however, the flavor diversity in sour congee of different foxtail millet varieties and key flavor-related metabolic pathways have yet to be thoroughly evaluated.. This study analyzed the physicochemical properties, taste components, and aroma compounds of six millet varieties used in sour congee production.. Results showed that flavor differences arose from compound concentrations rather than types.

Article Title: Differences in odor-active compounds and non-volatile precursors between spray-dried and freeze-dried Spirulina platensis revealed by GC×GC-TOFMS-O and UPLC-MS/MS.
Article Snippet: The effects of freeze-drying and spray-drying on odorants and precursors in Spirulina platensis (Sp) cultivated in different environments (gj: glass jar; rp: raceway pond; cp: circular pond) were investigated.. Ninety-four odorants were identified, and hexanal, (Z)-4-decenal, (E, E)-2,4-decadienal, β-cyclocitral, β-ionone, dimethyl trisulfide exhibited higher flavor dilution factors (≥ 81).. Spray-drying increased pyrazines and terpenoids formation, enhancing roasted and seaweed-like odors, whereas freeze-drying retained higher levels of aldehydes and acids, causing fishy and rancid odors.

Article Title: Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Article Snippet: Soil organic carbon (SOC) sequestration is crucial in sustaining agroecosystem productivity.. However, the mechanism through which microbial functional gene assemblages and rhizosphere metabolites drive SOC sequestration remains elusive.. Ten-year field experiments examined how straw mulching (0 and 7500 kg ha 1) with nitrogen (0, 120, and 180 kg N ha 1) reshape microbial functional potential, drive soil carbon sequestration, and enhance annual crop productivity in the wheat–maize rotation system.

Article Title: Planthopper-induced volatiles suppress rice plant defense by targeting Os4CL5-dependent phenolamide biosynthesis.
Article Snippet: The mean weight of REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins p-Coumaric acid Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-98-4 N-Feruloylputrescine Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-13-3 Deposited data RNA-seq data This paper NCBI GEO: PRJNA1276156 Raw analysis data This paper; Mendeley Data https://doi.org/10.17632/c7ftgzyc84.1 Experimental models: Organisms/strains Rice strain (Minghui63) China Rice Data Center N/A Rice strain (Zhonghua11) Biogle Biotech Co., Ltd, Jiangsu, China N/A Rice strain (aoc mutant) Henan University N/A Rice strain (ospal6 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101768B06 Rice strain (os4cl5 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101529A08 Oligonucleotides Primers for quantitative real-time PCR This paper Table S5 Software and algorithms Primer 6 Premier Biosoft International, Palo Alto CA, USA http://www.premierbiosoft.com/primerdesign/ SPSS 26.0 IBM SPSS, Somers, NY, USA https://www.ibm.com SIMCA 14.1 Umetrics, Umeå, Sweden https://www.sartorius.com/en/products/process- analytical-technology/data-analytics-software/ mvda-software/simca Metaboanalyst 5.0 N/A https://www.metaboanalyst.ca/ ll OPEN ACCESS e1 Current Biology 35, 1–11.e1–e4, July 21, 2025 Article the BPH nymphs on one plant was considered as a biological replicate, and a total of 35-36 replicates were conducted for each treatment.

Article Title: An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy
Article Snippet: Principal component analysis (PCA) was conducted with SIMCA 14.1 (Umetrics AB, Umea, Sweden).

Article Title: Advancing freshness classification of freshly squeezed fruit juice via integrated multivariate analysis and machine learning approaches.
Article Snippet: In this study, multivariate analysis (MVA) and machine learning (ML), combined with UHPLC-HRMS, were used to evaluate the freshness of apples for juice production based on the analysis of freshly squeezed apple juice.. A total of eight stages of apple juice, representing varying levels of freshness, were examined.. Unsupervised MVA techniques, including PCA and Spearman rank correlation heatmap, revealed biochemical changes in the apple juice composition as rotten progressed.

Article Title: Metabolic dynamics of litchi pericarp and pulp during browning: Unraveling differential profiles through temporal clustering and untargeted metabolomics
Article Snippet: Chemometric modeling (PCA, OPLS-DA) was carried out using SIMCA 14.1 (Umetrics AB, Umeå, Sweden), with statistical significance assessed through nonparametric Mann–Whitney U tests ( P < 0.05) performed in SPSS 26.0 (SPSS Inc., Chicago, Illinois, USA).

Article Title: Physicochemical properties, aroma compounds, non-volatile metabolites and their potential correlation in Wickerhamomyces anomalus- fermented Sichuan-style sausage
Article Snippet: Principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed with SIMCA 14.1 (Umetrics, Umea, Sweden).

Real-time Polymerase Chain Reaction:

Article Title: Exploring the flavor characteristics and key flavor-related metabolic pathways in sour congee of different foxtail millet varieties
Article Snippet: Sour congee is a traditional non-alcoholic fermented grain food in China; however, the flavor diversity in sour congee of different foxtail millet varieties and key flavor-related metabolic pathways have yet to be thoroughly evaluated.. This study analyzed the physicochemical properties, taste components, and aroma compounds of six millet varieties used in sour congee production.. Results showed that flavor differences arose from compound concentrations rather than types.

Article Title: Differences in odor-active compounds and non-volatile precursors between spray-dried and freeze-dried Spirulina platensis revealed by GC×GC-TOFMS-O and UPLC-MS/MS.
Article Snippet: The effects of freeze-drying and spray-drying on odorants and precursors in Spirulina platensis (Sp) cultivated in different environments (gj: glass jar; rp: raceway pond; cp: circular pond) were investigated.. Ninety-four odorants were identified, and hexanal, (Z)-4-decenal, (E, E)-2,4-decadienal, β-cyclocitral, β-ionone, dimethyl trisulfide exhibited higher flavor dilution factors (≥ 81).. Spray-drying increased pyrazines and terpenoids formation, enhancing roasted and seaweed-like odors, whereas freeze-drying retained higher levels of aldehydes and acids, causing fishy and rancid odors.

Article Title: Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Article Snippet: Soil organic carbon (SOC) sequestration is crucial in sustaining agroecosystem productivity.. However, the mechanism through which microbial functional gene assemblages and rhizosphere metabolites drive SOC sequestration remains elusive.. Ten-year field experiments examined how straw mulching (0 and 7500 kg ha 1) with nitrogen (0, 120, and 180 kg N ha 1) reshape microbial functional potential, drive soil carbon sequestration, and enhance annual crop productivity in the wheat–maize rotation system.

Article Title: Planthopper-induced volatiles suppress rice plant defense by targeting Os4CL5-dependent phenolamide biosynthesis.
Article Snippet: The mean weight of REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins p-Coumaric acid Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-98-4 N-Feruloylputrescine Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-13-3 Deposited data RNA-seq data This paper NCBI GEO: PRJNA1276156 Raw analysis data This paper; Mendeley Data https://doi.org/10.17632/c7ftgzyc84.1 Experimental models: Organisms/strains Rice strain (Minghui63) China Rice Data Center N/A Rice strain (Zhonghua11) Biogle Biotech Co., Ltd, Jiangsu, China N/A Rice strain (aoc mutant) Henan University N/A Rice strain (ospal6 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101768B06 Rice strain (os4cl5 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101529A08 Oligonucleotides Primers for quantitative real-time PCR This paper Table S5 Software and algorithms Primer 6 Premier Biosoft International, Palo Alto CA, USA http://www.premierbiosoft.com/primerdesign/ SPSS 26.0 IBM SPSS, Somers, NY, USA https://www.ibm.com SIMCA 14.1 Umetrics, Umeå, Sweden https://www.sartorius.com/en/products/process- analytical-technology/data-analytics-software/ mvda-software/simca Metaboanalyst 5.0 N/A https://www.metaboanalyst.ca/ ll OPEN ACCESS e1 Current Biology 35, 1–11.e1–e4, July 21, 2025 Article the BPH nymphs on one plant was considered as a biological replicate, and a total of 35-36 replicates were conducted for each treatment.

Article Title: An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy
Article Snippet: Principal component analysis (PCA) was conducted with SIMCA 14.1 (Umetrics AB, Umea, Sweden).

Article Title: Advancing freshness classification of freshly squeezed fruit juice via integrated multivariate analysis and machine learning approaches.
Article Snippet: In this study, multivariate analysis (MVA) and machine learning (ML), combined with UHPLC-HRMS, were used to evaluate the freshness of apples for juice production based on the analysis of freshly squeezed apple juice.. A total of eight stages of apple juice, representing varying levels of freshness, were examined.. Unsupervised MVA techniques, including PCA and Spearman rank correlation heatmap, revealed biochemical changes in the apple juice composition as rotten progressed.

Article Title: Metabolic dynamics of litchi pericarp and pulp during browning: Unraveling differential profiles through temporal clustering and untargeted metabolomics
Article Snippet: Chemometric modeling (PCA, OPLS-DA) was carried out using SIMCA 14.1 (Umetrics AB, Umeå, Sweden), with statistical significance assessed through nonparametric Mann–Whitney U tests ( P < 0.05) performed in SPSS 26.0 (SPSS Inc., Chicago, Illinois, USA).

Article Title: Physicochemical properties, aroma compounds, non-volatile metabolites and their potential correlation in Wickerhamomyces anomalus- fermented Sichuan-style sausage
Article Snippet: Principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed with SIMCA 14.1 (Umetrics, Umea, Sweden).

Software:

Article Title: Exploring the flavor characteristics and key flavor-related metabolic pathways in sour congee of different foxtail millet varieties
Article Snippet: Sour congee is a traditional non-alcoholic fermented grain food in China; however, the flavor diversity in sour congee of different foxtail millet varieties and key flavor-related metabolic pathways have yet to be thoroughly evaluated.. This study analyzed the physicochemical properties, taste components, and aroma compounds of six millet varieties used in sour congee production.. Results showed that flavor differences arose from compound concentrations rather than types.

Article Title: Differences in odor-active compounds and non-volatile precursors between spray-dried and freeze-dried Spirulina platensis revealed by GC×GC-TOFMS-O and UPLC-MS/MS.
Article Snippet: The effects of freeze-drying and spray-drying on odorants and precursors in Spirulina platensis (Sp) cultivated in different environments (gj: glass jar; rp: raceway pond; cp: circular pond) were investigated.. Ninety-four odorants were identified, and hexanal, (Z)-4-decenal, (E, E)-2,4-decadienal, β-cyclocitral, β-ionone, dimethyl trisulfide exhibited higher flavor dilution factors (≥ 81).. Spray-drying increased pyrazines and terpenoids formation, enhancing roasted and seaweed-like odors, whereas freeze-drying retained higher levels of aldehydes and acids, causing fishy and rancid odors.

Article Title: Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Article Snippet: Soil organic carbon (SOC) sequestration is crucial in sustaining agroecosystem productivity.. However, the mechanism through which microbial functional gene assemblages and rhizosphere metabolites drive SOC sequestration remains elusive.. Ten-year field experiments examined how straw mulching (0 and 7500 kg ha 1) with nitrogen (0, 120, and 180 kg N ha 1) reshape microbial functional potential, drive soil carbon sequestration, and enhance annual crop productivity in the wheat–maize rotation system.

Article Title: Planthopper-induced volatiles suppress rice plant defense by targeting Os4CL5-dependent phenolamide biosynthesis.
Article Snippet: The mean weight of REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins p-Coumaric acid Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-98-4 N-Feruloylputrescine Yuanye Biotech Co., Ltd, Shanghai, China Cat# 501-13-3 Deposited data RNA-seq data This paper NCBI GEO: PRJNA1276156 Raw analysis data This paper; Mendeley Data https://doi.org/10.17632/c7ftgzyc84.1 Experimental models: Organisms/strains Rice strain (Minghui63) China Rice Data Center N/A Rice strain (Zhonghua11) Biogle Biotech Co., Ltd, Jiangsu, China N/A Rice strain (aoc mutant) Henan University N/A Rice strain (ospal6 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101768B06 Rice strain (os4cl5 mutant) Biogle Biotech Co., Ltd, Jiangsu, China Cat# BG101529A08 Oligonucleotides Primers for quantitative real-time PCR This paper Table S5 Software and algorithms Primer 6 Premier Biosoft International, Palo Alto CA, USA http://www.premierbiosoft.com/primerdesign/ SPSS 26.0 IBM SPSS, Somers, NY, USA https://www.ibm.com SIMCA 14.1 Umetrics, Umeå, Sweden https://www.sartorius.com/en/products/process- analytical-technology/data-analytics-software/ mvda-software/simca Metaboanalyst 5.0 N/A https://www.metaboanalyst.ca/ ll OPEN ACCESS e1 Current Biology 35, 1–11.e1–e4, July 21, 2025 Article the BPH nymphs on one plant was considered as a biological replicate, and a total of 35-36 replicates were conducted for each treatment.

Article Title: An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy
Article Snippet: Principal component analysis (PCA) was conducted with SIMCA 14.1 (Umetrics AB, Umea, Sweden).

Article Title: Advancing freshness classification of freshly squeezed fruit juice via integrated multivariate analysis and machine learning approaches.
Article Snippet: In this study, multivariate analysis (MVA) and machine learning (ML), combined with UHPLC-HRMS, were used to evaluate the freshness of apples for juice production based on the analysis of freshly squeezed apple juice.. A total of eight stages of apple juice, representing varying levels of freshness, were examined.. Unsupervised MVA techniques, including PCA and Spearman rank correlation heatmap, revealed biochemical changes in the apple juice composition as rotten progressed.

Article Title: Metabolic dynamics of litchi pericarp and pulp during browning: Unraveling differential profiles through temporal clustering and untargeted metabolomics
Article Snippet: Chemometric modeling (PCA, OPLS-DA) was carried out using SIMCA 14.1 (Umetrics AB, Umeå, Sweden), with statistical significance assessed through nonparametric Mann–Whitney U tests ( P < 0.05) performed in SPSS 26.0 (SPSS Inc., Chicago, Illinois, USA).

Article Title: Physicochemical properties, aroma compounds, non-volatile metabolites and their potential correlation in Wickerhamomyces anomalus- fermented Sichuan-style sausage
Article Snippet: Principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed with SIMCA 14.1 (Umetrics, Umea, Sweden).



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